- OEM / SystemsOEM Systems | Precision Components | Automation Sub-SystemsPI offers 1000’s of proven, off-the-shelf precision motion products that can be quickly modified for the OEM or into a custom automation sub-system.
- Meeting the Demands of OEMsOEM Systems | Precision Components | Automation Sub-SystemsPI has a long track record of working with OEMs in the most demanding industries from Semiconductor Technology to Medical Design – industries where product performance, quality, and the ability to ramp up quickly are not the only parameters required to satisfy the customer's demands. Working with technology leaders all around the world forces you to continuously improve your yield, process, and product performance. And unless your quality is outstanding, you cannot become a key supplier to major US, European, and Japanese companies in the Optics, Photonics, Semiconductor, and Automotive industry.
- Engineered Motion / Automation Sub-SystemsPrecision Automation Solutions | Engineered SystemsPI is a supplier of high-end precision motion systems and makes use of own drive components and high-precision positioners to build customized positioning and automation sub-systems —“motion engines”—for our customers. With the largest portfolio of precision motion technologies in the industry, PI engineers have the best foundation to find a solution that matches your requirements in terms of precision, quality and budget – in a timeframe that works for you.
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- ProductsPrecision Motion Technologies | Positioning SystemsOverview of the Broadest & Deepest Portfolio of Precision Motion and Automation Technologies from Piezo to Air Bearings and Linear Motors
- Products: Overview, New, Finder, ShopFind Precision Positioning Solutions Quickly - Product Finder | PI USAWith thousands of standard products and customization available, PI has the motion control positioning product solution for your application.
- Products OverviewProducts OverviewOverview of the Broadest & Deepest Portfolio of Precision Motion and Automation Technologies from Piezo to Air Bearings and Linear Motors
- New ProductsNew Motion Control & Precision Positioning Products | PI USALearn about the latest innovations in motion control and nanopositioning components and systems.
- Product FinderUse the PI Product Finder - it's fast and easy!Select the product type specified by the axes of motion required. Selection of more criteria expands or shortens the list of results. Select more than one filter at at time, for example, to find positioning stages designed for higher load capacity, too.
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- Air Bearings & Ultra High Precision StagesAir Bearing Stages | Motorized | Linear | RotaryAir bearings provide advantages over mechanical bearings when vibration-free motion is required, highly constant velocity control is crucial, and when angular repeatability and geometric performance must be optimal. Air bearing stages (linear, rotary, and spherical) replace mechanical contact by a thin air film, avoiding wear, friction, vibration, and hysteresis effects.
- Miniature Positioning StagesMiniature Positioning Stages | Supplier | ManufacturerCompact positioning stages are crucial for the miniaturization process in cutting-edge research and industrial applications, for test & measurement, optical and opto-mechanical alignment, and component assembly. PI provides the largest portfolio of miniature stages, including high-speed linear motor stages, economical stepper motor units, and ultra-compact piezo motor positioners.
- Motorized Stages: Linear, Rotary, XYMotorized Stages | Positioning | ManufacturerPI offers the broadest and deepest range of precision motion technologies for micro and nano precision applications. Our engineers work with our customers to find the best drive and bearing technology for each individual application. Having access to multiple drive and positioning technologies allows an open discussion with a better outcome for the customer.
- Overview - Motorized Linear/Rotary StagesOverview - Motorized Linear/Rotary Stages
- Linear StagesLinear Stages - Precision Positioning Solutions | PI USASeveral types of motorized precision linear translation stages | PI USA
- Fast Linear Motor Stages and ActuatorsOverview: Linear Stage, Linear Motor Driven, Fast Brushless Motor Positioning Stages | PI USABrushless linear motor-driven stages provide high speed, precision and long life.
- Z-Stages (Vertical Motion)Vertical Linear Stages – Precision Motorized Z-Positioners | PI USA
- XY StagesXY Stages – 2-Axis Motorized Precision Positioning Stages | PI USASeveral types of planar XY stages: Direct-driven stages, ball-screw stages and air bearing planar XY stages
- XYZ StagesXYZ Stage - Multi-Axis Precision Motorized Stages
- Rotary Stages / GoniometersPrecision Rotation Stage, High Resolution Rotary Positioners, Rotation Tables, Goniometers, by PI USASeveral types of motorized rotation stages: Direct-driven stages, ball-bearing stages and air bearing stages
- Heavy Duty Stages / Industrial AutomationHigh Speed / Performance Positioning Stages for Automation - Linear Stages | Rotary Stages | PI USAHigh performance motorized stages, designed for heavy duty applications in industrial precison automation.
- Sub-Systems for AutomationSYS > Engineered Motion/Automation Sub-SystemsThe PI group employs over 1,200 people in 15 countries and runs engineering and manufacturing centers on 3 continents. Select from the broadest portfolio of precision motion technologies, including piezoelectric and air bearing systems, with 1,000’s of standard products or have our engineers provide you with a custom solution.
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- Linear ActuatorsActuators | Precision | Linear | Actuator SystemA precision linear actuator is a positioning device that provides motion in 1 degree of freedom. PI designs and manufactures a variety of precision linear actuators (pushers) including economical stepper-motor driven actuators, high-speed linear motor types for automation and nanometer precise piezo-motor actuators.
- Gantries / Cartesian RobotsGantry Stages | Gantries | Cartesian RobotA gantry precision positioning stage is sometimes called a linear robot or Cartesian robot. Gantries typically provide motion in 2 or 3 linear degrees of freedom (X-Y and X-Y-Z) and are often used for pick and place applications, 3D printing or laser machining, and welding applications.
- 6-Axis Hexapods / Parallel PositionersHexapod Positioner | Six DOF | Stewart PlatformsHexapod positioners are often referred to as Stewart Platforms. A hexapod is based on a 6-axis (XYZ, Pitch, Roll, Yaw) actuator system arranged in parallel between a top and bottom platform. PI parallel kinematics (PKM) precision positioning systems have many advantages over serial kinematics stages, such as lower inertia, improved dynamics, smaller package size and higher stiffness. In addition hexapods are more flexible than conventional 6 axis positioners.
- 6-Axis Hexapods / Parallel Positioners6-Axis Hexapods / Parallel Positioners
- Control of Hexapod / Stewart Platforms: Hexapod Motion Controllers & Simulation Software6DOF Motion Platforms | Hexapod Controllers & Simulation Software | Stewart Platform | ManufacturerControllers, software and accessories for Hexapod Stewart platforms and parallel kinematic motion systems | PI USA
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- Piezo Flexure Nanopositioning StagesNanometer Precision: Piezo Stages for Nanopositioning, Piezo Nanopositioners, Piezo Flexure Scanning Stages | PI USAPI offers the broadest and deepest portfolio of nanometer precision motion technologies, from piezo-driven nanopositioning and scanning stages to motorized 6-axis hexapod positioning systems.
- Overview - Piezo Flexure StagesOverview - Piezo Flexure Stages
- Linear Piezo Flexure StagesLinear Piezo Stages for Nanopositioning – Flexure-Guided Precision NanoPositioners | PI USALargest selection of frictionless, high performance piezo-stack-driven flexure linear nanopositioning stages | PI USA
- Vertical & Tip/Tilt Piezo StagesPiezo Z-Stage, Piezo Z-Tip-Tilt Platform. Flexure Guided Nanopositioning Stages| PI USALarge selection of Piezo Z-Stages and Tip/Tilt scanners with nanometer precision | PI USA
- Fast Steering Mirrors & Tip/Tilt PlatformsPiezo Steering Mirrors | Active Optics
- Nanofocus Lens ScannersFast Piezo Focus Lens Positioners and Scanners – Piezo Flexure Guided Precision Positioners | PI USALargest Selection of Nano-Focus drives for microscope lenses – flexure-guided precision positioners
- XY Piezo Flexure StagesPiezo Stages | XY | Nanopositioning StagesLargest selection of integrated XY piezo flexure stages with nanometer precision.
- XYZ Piezo Flexure StagesXYZ Piezo Nanopositioning Stages – Flexure Guided 3-Axis Precision Positioners | PI USALargest selection of integrated XYZ piezo flexure stages with nanometer precision.
- 6-Axis Piezo Flexure Stages6-Axis Piezo Nanopositioning Stages – Flexure Guided Precision Positioners | PI USAPiezo-driven fast steering mirrors (FSM) achieve nanoradian resolution and high bandwidth.
- Tutorial - Piezo NanopositioningNanometer Precision: Nanopositioning Basics Tutorial. Piezo Nanopositioners, Scanning Stages, Flexure Guided Positioners | PI USAThere are several ways to achieve nanometer precision motion. The best positioning systems avoid friction all together, in both the drive system (motor) and in the guiding system (bearings). Frictionless bearings also avoid the bearing rumble caused by balls and rollers and provide vibration-free motion with highly constant velocity.
- Overview - Piezo Flexure Stages
- Piezo Motors: Stages & ActuatorsPiezo Motors | Linear Motor Positioners | ManufacturerPiezo Motors are intrinsically vacuum compatible, non-magnetic and self locking at rest, providing long travel compared to traditional piezo mechanisms. The individual drive concepts are optimized for different applications, they differ in their design, size, cost, force & speed and other performance parameters.
- Overview - Piezo Motors (Stages/Actuators)Overview - Piezo Motors (Stages/Actuators)
- Actuators with Piezo MotorsCompact precision linear actuators stages with several types of piezo motor drives – ultrasonic, stick-slip, piezo-walk, piezo-ratchet. | PI USA
- Linear Stages with Piezo MotorsPrecision linear stages with several types of piezo motor drives – ultrasonic, stick-slip, piezo-walk, piezo-ratchet. | PI USA
- XY Stages with Piezo MotorsXY piezo motor linear stages with several types of precision piezo motor drives – ultrasonic, stick-slip, piezo-walk | PI USA
- XY Piezo Flexure StagesXY Piezo Flexure StagesHigh-precision 2-axis nanopositioning systems integrate PICMA® piezo actuators for maximum reliability. Repeatable, drift-free positioning with optimal stability is possible by the use of high-quality nanometrology sensors.
- Rotary Stages with Piezo MotorsRotary piezo motor stages with several types of precision piezo motors– ultrasonic, stick-slip (inertia), | PI USA
- Tutorial - Piezo Motion ControlWhy All Piezo Motors are NOT Created Equal: The piezoelectric effect for precision motion control - PI Physik Instrumente.The demand for higher speed and/or precision in fields such as bio-nanotechnology, semiconductors, metrology, data comm, and photonics keep pushing manufacturers to come up with innovative drive technologies.
- Overview - Piezo Motors (Stages/Actuators)
- Piezo Transducers & ActuatorsPiezo Actuator | Piezo Transducer | ManufacturerPiezoelectric translators (transducers) are precision ceramic actuators which convert electrical energy directly into linear motion with high speed, force and virtually unlimited resolution. These actuators are used in every modern high tech field from semiconductor test & inspection to super-resolution microscopy, bio-nanotechnology and astronomy/aerospace technology.
- Piezo Actuators & Transducers: Stacks, Chips, Benders, Tubes, Spheres, Shear…Piezo Actuators & Transducers: Stacks, Chips, Benders, Tubes, Spheres, Shear…
- Value-Added Piezo Transducers & Piezo AssembliesValue Added Piezo Assemblies: Transducers, Actuators, Sensors, Manufactured by PI CeramicDeveloping and manufacturing piezo ceramic materials and components are complex processes. PI Ceramic - PI’s piezo material design and manufacturing facility - boasts several decades of experience as well as the right tools for rapid prototyping of custom engineered piezo components and assemblies. From the formulation of advanced piezo materials to the processing steps such as cutting, milling, grinding, and the precision assembly, every stage is controlled by our engineers and product specialists.
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- Piezo Actuators & Transducers: Stacks, Chips, Benders, Tubes, Spheres, Shear…
- Microscopy, Bio-Imaging, Life SciencesHigh Precision Microscope Stages, Piezo Lens Scanners, Tools for Bio-Imaging | PI-USAPiezo nano-positioning stages are essential tools for high-resolution microscopy, such as Super Resolution Microscopy or AFM. Their sub-atomic resolution and extremely fast response allow researchers to create higher-quality images faster. PI provides a large variety of fast Z-Stages and collar piezo objective positioners for 3D imaging (Z-stack acquisition), deconvolution, and fast focusing applications.
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- Applications: Life Sciences / MedicalPrecision motion control for medical engineering and life sciences applications | PI USA
- Stages for Microscopy & Bio-Imaging
- Photonics Alignment SolutionsActive Photonics Alignment | Optics Alignment | SolutionsPI provides a variety of innovative fiber alignment systems from motorized fiber positioners to automated optic and photonic alignment such as used in telecommunication, data commumication and for packaging / automation. In addition to fiber-based applications, fast steering systems for free-space-optical communication are also available. Products range from motorized 6D micromotion alignment systems for industrial photonics automation, through ultra-fast piezoelectric scanning & alignment modules to modular devices with manual control for laboratory test setups. All motorized systems come with extensive software for easy setup and integration.
- Vacuum Positioning Stages & ActuatorsVacuum / UHV Compatible Stages - Linear & Rotary Positioners for Vacuum, Wide Temperature Ranges | PI USAPI miCos has extensive experience in the design and manufacturing of vacuum and high vacuum compatible precision optomechanical positioning equipment for low temperature and wide temperature ranges. We provide translation stages, vertical linear stages, rotation stages, XY stages and complex multi-axis positioning systems in vacuum spec.
- VacuumProduct Series with Vacuum-Ready ItemsPI offers specific catalogue items for selected product series that are already suitable for high vacuum (HV) or ultra-high vacuum (UHV).
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- Controllers, Drivers, Motion SoftwareMotion Controllers, Piezo Drivers-High Voltage Amplifiers, and Motion Software Overview | PI USA
- Overview - Controllers & Motion SoftwareOverview - Controllers & Motion Software
- Piezo Controller, Driver, Nanopositioning Controller, High-Voltage Amplifier, Piezo Power Supply by PI USAPiezo Drivers | Piezo Motion Controllers | ManufacturerA piezo controller or driver is used to control the motion of a piezo positioning device. There are open and closed loop controllers. Open-loop controllers are often referred to as piezo driver or even piezo power supply. Closed-loop controllers are divided in two basic types: analog-servo and digital servo controllers.
- Controllers/Drivers for Motorized StagesMotion Controller | Drivers | Positioning SystemsPI provides a large variety of hardware & software solutions for high precision motion control. Our portfolio spans from integrated compact single axis servo controllers / drivers, such as popular Mercury-class motion controllers, to complex multi-axis systems for parallel-kinematics positioners, such as hexapods.
- ACS Motion ControlACS Motion Control for Industrial AutomationWe recommend the controllers of our partner, ACS Motion Control especially for automation with industrial standards. Ask us about your integrated solution!
- Software - Motion Control SoftwareMotion Control Software | Software Tools | Positioning SolutionsFor LabView, C++, VB, Matlab, Image Acquisitiong Packages, NI DAC Cards, ..... PI provides high-level, robust, easy-to-use software tools for fast, seamless integration of motion systems into application control software.
- Overview - Controllers & Motion Software
- Capacitive SensorsNanometer Resolution: Capacitance Sensors for Nano-Measuring, Nano-Metrology | PIA capacitive sensor is a proximity sensor that detects nearby objects by their effect on the electrical field created by the sensor.
- Accessories: Plates, Brackets, CablesAdapters and Cables for PI Precision Motion ComponentsStandardization is common with adapter plates and brackets, but we can create a custom accessory to fit your application system. PI products ship with the required cables. Customization is always an option.
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- Tech BlogPI Blog / Tech Articles on Advancements in Precision Motion Control, Automation and Piezo Technology | PI USAPI’s tech blog offers 50 years of insight into innovative applications of precision motion control, nanopositioning, and micropositioning in industry, science, and research. We hope the PI blog is an enjoyable and informative resource, and a starting-point for innovation across disciplines.
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- Motion Control SoftwareMotion Control SoftwarePI provides high-level, robust, easy-to-use motion control software tools for fast, seamless integration of motion systems into application control software. Supported programming languages and applications include LabView, C++, VB, Matlab, Image Acquisitioning Packages, NI DAC Cards, ...
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Flamingo? It automatically reminds you of pink feathers, an accentuated beak, and the unique silhouette of a representative of the genus "phoenicopteridae", which always stands on one leg while sleeping.
This latter fact exactly served Professor Dr. Jan Huisken, Research Group Leader and Director of the Medical Engineering Department at Morgridge Institute for Research in Madison, WI, as the name-giving feature for the special light sheet microscopes developed by him and his team. The silhouette of these microscopes reminds us of this sleeping exotic bird.
The goal of the Flamingo project, which is supported by several sponsors, is to make these modular microscopes available to researchers ‒ in their laboratories ‒ free of charge.
The rendering of a compact Flamingo light sheet microscope with L-SPIM configuration (see text) reminds us of the one-legged sleeping bird. (Image: Image: Morgridge Institute for Research, Madison, WI) Light Sheet Microscopy: Technology and Advantages
In Light Sheet Fluorescence Microscopy (LSFM), illumination and detection are two separate optical systems that are perpendicular to each other. The laser beam used to illuminate the sample is focused in one direction and forms a light sheet that illuminates a thin layer of the sample. The fluorescent light that is emitted in this plane is captured and detected by an objective lens.
By separating the illumination from the detection, the microscope can practically be built "around the experiment". Instead of mounting samples in between microscope slide and coverslip, they are immersed in a hydrogel and placed in a cylindrical sample chamber inside the microscope. There, the conditions are close to physiological and so even continuous recordings from living specimens are possible.
Sample Positioning is Particularly Important
The positioning of the sample plays a special role since the sample is moved linearly or rotated as required. For this purpose, PI (Physik Instrumente) supplies several subsystems. "We are proud to be among the seed supporters and sponsors of Jan Huisken’s groundbreaking Flamingo project," says Dr. Thomas Bocher, the Head of Segment Marketing 'Microscopy & Life Sciences' at PI. "For the Flamingo project, reliability and precision of modules are key factors. This means, high precision, fast movements, and a compact size of the drives together with high quality production standards and services from PI make the difference."
Low Phototoxicity
"LSFM is a very powerful and flexible platform for gentle in vivo imaging offering low phototoxicity and fast image acquisition," Jan Huisken summarizes the advantages of the technology. Because of the gentle "treatment" of the sample, LSFM is predestined for the examination of living organisms. One of the research goals of this technology is to gain a better understanding of highly dynamic processes such as embryonic morphogenesis (i.e., the development of organisms, organs, and organelles).
Light sheet microscopy provides fascinating images of living organisms and of time sequences of developmental processes. Zebrafish recorded by Alyssa Graves with Flamingo #1. (Image: Morgridge Institute for Research, Madison, WI) Modular Design
In order for the implementation to work, some conditions had to be met: The system had to be very robust, easy to assemble, and simple to operate. The solution: A straightforward, uncomplicated design with proven standard components, a small footprint, and costs as low as possible. This also allows for different, application-specific designs: In the T-SPIM design, the sample is illuminated from two opposing optics for a more uniform illumination. The addition of a second detection path results in the X-SPIM design.
Sample Positioning within the Microscope
L-505 compact linear stage with folded drivetrain (left) Learn more One of the most common application in Light Sheet Microcopy is the creation of Z stacks with which the sample can be wholly depicted in three dimensions. For this purpose, the sample is moved in the Z direction (that is, along the optical axis of the objective lens). For this task, PI contributes compact linear stages of the L-505 type. These very compact linear stages have a folded drivetrain, DC motors with gearhead, linear encoders, and offer 26mm travel range at a bidirectional repeatability of ±250nm. The stage also excels by a high stiffness and guiding accuracy due to ball guides.
Ultrasonic piezo motors offer a completely self-developed operating principle, they are based on PI's own piezo production and have proven themselves with PI's customers. This operating principle allows for very low response times as well as highly accurate positioning. Learn more Rotating the specimen can be useful in several scenarios. Often, researchers want to be able to image their sample from just the right angle (side view, top view etc.) or want to image an organ that’s only visible from certain angles (like the heart). The other big application for rotation is so-called multi-view imaging, where z-stacks are recorded from multiple angles, e.g. 6 angles covering 360 degrees, and then the useful parts of each dataset are fused to generate one 3D image that covers the entire sample. This is particularly useful for larger samples as the sample itself scatters, refracts and absorbs the light, affecting the illumination and detection quality of structures deep inside the sample. Therefore several angles are needed to capture all the details.
The rotation of the sample is supported by the U-628 ultrasonic piezo-motor-driven rotation stage from PI. It offers fast movement of up to 720°/s at a minimum step size of 51 µrad and a bidirectional repeatability of ±102µrad.
Motivation and Philosophy Behind the Flamingo Project
The latest Flamingo Microscope, with the (1) L-505 linear stages and (2) U-628 rotary stage visible. Jan Huisken, co-inventor of Light Sheet Microscopy when working on his PhD at the EMBL Heidelberg (Germany), has recently started this project and states, "We aim to democratize high-end light microscopy, bringing it to campuses and labs for free. We think this will be especially useful for reproducing scientific results, something increasingly important to science." Michael Weber, the Field Application Specialist for the US East Coast in the Flamingo project adds, "We’re turning the idea of a research imaging facility upside down. We want to bring the microscope as close to the sample as possible, rather than biologists bringing their delicate samples to us." Bringing the microscope to the biologist has one major advantage: Neither the biologist, nor the sample have to travel. Since most of the samples are highly sensitive to changing environmental conditions (e.g., gravity, humidity, temperature), this approach helps researchers to focus on their work rather than caring for logistics.
The project also aims to intensify the dialogue between system developers and users in order to further the development of the LSFM technology.
Outlook
The second Flamingo system has already been set up on the East Coast of the United States. In the months and years to come, several dozens of Flamingos will be built to meet the enormous demand for state-of-the-art light sheet microscopes for research in the US and many other countries around the world. Thomas Bocher states, "PI will continue to support this philanthropic endeavor."
Update – Prof. Huisken wins the 2020 Lennart Nilsson Award
Stockholm, Sweden – September 2020 – Prof Huisken wins the 2020 Lennart Nilsson Award for his developments and creative use of light-sheet microscopy, also called SPIM (selective plane illumination microscopy). This international award is bestowed annually upon an individual in recognition of outstanding contributions within the realm of scientific imaging and acknowledges ingenious scientific breakthroughs. Dr. Huisken's work has led to observations of life that were previously impossible to imag(in)e. His videos and images of live organisms are spectacular both in their scientific content and their artistic qualities.
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